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You should consider target enrichment (target capture) if you are analyzing a subsection of a genome or performing deep sequencing to identify rare mutations.
This helps you to reserve sequencing capacity for the region(s) of interest and reduce the sequencing cost and time associated with data analysis.
Our xGen™ Custom Hyb Panel probes are practical because they can be used on their own, or for supplementing other capture panels to expand the target region and improve enrichment.